The planes fired a dozen missiles at an alleged hideout some 30km (20 miles) from the region's main town, Miranshah.The US has stepped up pressure on Pakistan's government since linking a failed car bombing in New York to the Pakistani Taliban.North Waziristan has been the focus of dozens of drone attacks since 2008.
The strikes have proved controversial, with hundreds of people, including civilians, being killed.
An unnamed Pakistani security official told the AFP news agency that the US drones had fired into the compound early on Tuesday.
"They targeted a compound and vehicles parked outside the house. According to the latest reports we have, a total of 14 militants were killed," the official said.
Reuters news agency quoted an unnamed security official as saying that "militants had cordoned off the area [and] so far they have retrieved 11 bodies from the debris".
The official said the death toll may rise as the "militants are still searching for bodies".The US has recently stepped up drone attacks in North and South Waziristan, where they believe many al-Qaeda and Taliban fighters find shelter.Over the past 18 months, Pakistan has publicly criticised drone attacks saying they fuel support for militants.
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